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Research Scientist

Bellevue, Wa, Washington, United States

Ref#: 3564

Date published: 12-Sep-2018

Intellectual Ventures (IV) Lab is part of Intellectual Ventures' efforts to support invention. IV Lab works on the very beginning stages of invention, validating the concept and refining the technology to demonstrate its potential for commercial or humanitarian use.  IV Lab believes in the power of independent and unconventional approaches to problems.  The broad range of Intellectual Ventures' invention activity provides IV Lab the opportunity for a breadth of expertise across fields including computer network security, computational modeling, electrical and mechanical engineering, software development, chemistry, microbiology, materials science, nanotechnology, physics, medical devices, and aerospace engineering.  IV Lab's unique environment has attracted veteran technologists and scientists from leading companies and renowned academic, government and private laboratories.

The Flow-Based Diagnostics Group (Flow Dx) at IV Lab is looking for a clinical assay Research Scientist experienced in assay chemistry and process development to support assay development on novel lateral-flow-based diagnostic platforms. The successful candidate will be expected to be flexible and ambitious to assume different roles and grow into new technical areas as needed. He or she needs to demonstrate a high level of initiative and ability to work in a team and in close alignment with his/her management.

The Flow Dx Group invents, designs, analyzes, prototypes, and tests new technologies to solve global health and global development challenges using a highly multidisciplinary approach. Staff members typically have advanced degrees in life sciences, chemistry, as well as Chemical, Electrical, Bio-  and Mechanical Engineering. The group is responsible for defining projects from available business problem information, and managing them all the way through early- to late-stage Research and Development, and often to the point of commercialization handoff.

  • Designing and evaluating point of care diagnostic assays and assay components. Scope includes primarily lateral flow immunochromatographic assays but may also include ELISA and microfluidics applications.
  • Owning and leading various aspects of the device and process design and development, as well as supporting other scientists in the lab.
  • Planning and carrying out tests to characterize system and subsystem performance using advanced analytical equipment and lab robots, and conduct evaluations using clinical samples in lab and field settings.
  • Develop and apply computational assay models to support R&D work
  • Develop new lab robot applications
  • Supporting external partner interfaces in co-development, or productization/design for manufacturing.
  • Will also lead initiatives and projects
  • May manage team members

Key Qualifications and Required Skills:

  • Experience with programming instruments for large/complex experiments (e.g., lab robots)
  • Familiarity with general programming languages (e.g. Python, R, Matlab)
  • Analytical mindset
  • Ability to troubleshoot complex systems
  • Understanding of statistics
  • Small hardware design and fabrication (e.g. use of SolidWorks) preferred
  • Finite element analysis (e.g. use of COMSOL) preferred
  • Understanding of fluid dynamics and microfluidics preferred
  • Familiarity with point-of-care diagnostics technologies preferred
  • Assay development expertise preferred
  • PhD in a bioanalytical science or equivalent with 3-5 years of lab experience, or highly relevant work history (5 plus years) in the areas listed above
  • Must be hands-on, capable of designing experiments, performing them, managing as well as supporting others to perform them, and building experimental systems.
  • Ability to work closely and effectively with other engineering disciplines and life scientists.
  • Substantial hands-on experience with clinical immunoassay R&D; experience with lateral flow assays and clinical diagnostic product development highly desired.
  • Experience and recent practice in lab settings and willingness and ability to productively work in lab settings for the majority of the work day. Experience with experimental and evaluation data analysis, biostatistics, and presentation of results in various formats.
  • Highly proactive and self-directed in identifying personal knowledge and/or skill gaps, and adept at acquiring the technical background needed to fill those gaps.

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